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diagnosis rheumatology hematology agglutinin anemia champs clinicopathology cryoglobulinemia cryoglobulins disease erythematosus extravascular fetal gammopathy glomerulonephritis hemolysis hemolytic hypertension hypoxia intravascular
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... #Low #Complement ... Mnemonic #diagnosis #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... tract, and often causes ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Diagnosis Algorithm ... Warm AIHA • Cold ... perfringens - Complement-Mediated ... • Cold AIHA
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Types: • Type ... • Low serum C4 complement ... #classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm
Vascular Joint Pain - Differential Diagnosis Algorithm - Constant Pain (Ischemia) - Acute Onset -
Vascular Joint Pain - Differential ... Diagnosis Algorithm ... Claudication) - Cold ... #Diagnosis #Algorithm ... #Orthopedics #Causes
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... Disease 3 Types ... Cryoglobulins (Vasculitic ... younger pts) Differential ... temperatures by fixing complement
Factors that May Affect Fetal Oxygenation - Differential Diagnosis Algorithm Excessive Uterine Activity: • Hyperstimulation • Placental
Oxygenation - Differential ... Diagnosis Algorithm ... Vasculopathy (SLE, Type ... #Diagnosis #Algorithm ... #Causes #Obstetrics
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... protein receptor type ... neurofibromatosis, vasculitis ... #Diagnosis #Differential ... #Causes
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... permanent alopecia Differential ... Kikuchi disease • Type-I ... RNP antibodies, Complement
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