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diagnosis rheumatology disease glomerular hematology monoclonal nephrology nephrotic testing workup agglutinin anemia biopsy cold cryoglobulinemia cryoglobulins diabetes differential dm2 dmii
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types: • Type ... • Type III Often ... • Low serum C4 complement ... • Vasculitis ... #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
Suggested algorithm ... with monoclonal gammopathy ... low-risk MGUS (IgG type ... #monoclonal #gammopathy ... #diagnosis #management
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
for monoclonal gammopathy ... of monoclonal gammopathy ... or alternative complement ... for ANCA-related vasculitis ... cryoglobulinemias (types
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
or alternative complement ... for monoclonal gammopathy ... of monoclonal gammopathy ... for ANCA-related vasculitis ... cryoglobulinemias (types
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Disease 3 Types ... Cryoglobulins (Vasculitic ... IgM monoclonal gammopathy ... temperatures by fixing complement
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm Lifestyle Modifications (Diet and Exercise) -> Start
Type 2 Diabetes ... Diagnosis and Management ... Algorithm Lifestyle ... #algorithm #DM2 ... #DMII #Classification
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
• Pancreas: Type ... aortitis, mimics vasculitis ... - ↑ IgE, ↓ complement ... • Classification ... IGG4 #Diagnosis #Management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... ANCA-associated vasculitis ... Kikuchi disease • Type-I ... RNP antibodies, Complement
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
Monoclonal Gammopathy ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis ... Types of MGRS-Associated
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