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diagnosis rheumatology differential large size small acute aki causes cryoglobulinemia ddxof erythematosus gammopathy glomerulonephritis im injury kidney lupus mgrs monoclonal
A System for Vasculitides #Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
A System for Vasculitides ... #Small #Medium ... #Vessel #Size #Classification ... #ANCA #Differential ... #Algorithm #Ddxof
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
MEDIUM VESSEL ... aortic aneurysm • Medium ... against MPO • Complement ... Serologies for Cryoglobulins ... #rheumatology #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Low serum C4 complement ... DDX: • ANCA (Antineutrophil ... • IgA vasculitis ... • Vasculitis ... diagnosis #types #classification
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
, medium vessel ... Medium vessel vasculitis ... large artery, medium ... basement membrane; ANCA ... #Large #Classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... (C-ANCA): GPA > ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... Vasculitis Vasculitis ... of medium vessels ... small vessels - ANCA-associated ... dermatomyositis #Size #Classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
primary condition MEDIUM ... : ANCA Associated ... Pauci Immune (ANCA ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... Glomerulonephritis / Vasculits ... : ANCA, ANA, Anti-GBM ... immunoglobulins, cryoglobulins ... #AKI #Workup #Algorithm
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... vasculitis, rheumatoid ... • Mesenteric vasculitis ... RNP antibodies, Complement
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
guide subtype classification ... tubulopathy) - Complement ... glomerulopathy) - Cryoglobulin ... formation causing vasculitis
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