37 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... antigen, leading to complement ... Complement activation ... #Classification ... Pathophysiology #Allergy #Diagnosis
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... immune deposits in glomeruli ... autoAb against type ... Glomerulonephritis #RPGN #Classification ... #Differential #Diagnosis
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... formation along glomerular ... staining (lg + complement ... MGPN • Complement ... MPGN #nephrology #diagnosis
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of types ... Allergen-specific lgE causes ... antigens, leading to complement ... they activate complement ... allergy #table #classification
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... diabetes)) #Glomerular ... Nephrotic #Syndromes #Classification ... Proteinuria #Nephrology #Diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Labs/Diagnosis: ... • Low serum C4 complement ... #types #classification
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
red - cells Non-glomerular ... - Diagnostic of ... glomerular disease ... - Any type of renal ... Microscopy #Atlas #key #diagnosis
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... or alternative complement ... infections are common causes ... cryoglobulinemias (types ... testing #workup #diagnosis
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
- Differential Diagnosis ... tubular acidosis (Types ... and 2, but not type ... Potassium #Table #Classification ... #Causes