12 results
diagnosis rheumatology renal management pulmonary syndromes anca clinicopathology cryoglobulinemia cryoglobulins ddxof disorders erythematosus gammopathy glomerulonephritis hematology igg4 im laboratory large
A System for Vasculitides #Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
A System for Vasculitides ... Diagnosis #IM #Rheum #Vasculitis ... #Vessel #Size #Classification ... #ANCA #Differential ... #Algorithm #Ddxof
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Rapidly Progressive ... staining): • Low Complement ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... proteinuria, rapidly progressing ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Syndromes and Mimics - Differential ... hemorrhage + rapidly progressive ... anti-GBM) 10%: - Low Complement ... - Normal Complement ... Syndromes #Mimics #Differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic ... #Differential #
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Diagnosis Algorithm ... system (node) with progression ... Lymphoproliferative #Disorders #Classification ... #algorithm
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • Low serum C4 complement ... • IgA vasculitis ... • Vasculitis ... diagnosis #types #classification
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... palpable purpura 2/2 vasculitis ... coagulopathy) • CBC w differential ... Path: rapidly progressive ... Renal #Syndromes #differential
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
inflammation -> progressive ... aortitis, mimics vasculitis ... - ↑ IgE, ↓ complement ... • Classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... permanent alopecia Differential ... ANCA-associated vasculitis ... RNP antibodies, Complement
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