14 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... , type 1 (50%-80% ... ), type II (80-90% ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome:
 - Acute poststreptococcal 
glomerulonephritis 
 - Rapidly progressive
Glomerular Diseases ... #Glomerular ... Nephrotic #Syndromes #Classification ... #Nephrology #Diagnosis ... Recommended Text: Nephrology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
Rapidly Progressive Glomerulonephritis ... autoAb against type ... staining #Glomerulonephritis ... #RPGN #Classification ... Differential #Diagnosis #Nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Membranoproliferative Glomerulonephritis ... formation along glomerular ... MGPN • Complement ... Membranoproliferative #Glomerulonephritis ... #MPGN #nephrology
Renal Tubular Acidosis (RTA) 
Type 1 - Failure of secretion
Type 2 - Bicarbonate wasting
Type 4 -
Acidosis (RTA) Type ... of secretion Type ... - Bicarbonate wasting ... #classification ... #nephrology #diagnosis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... antigen, leading to complement ... Complement activation ... Post-streptococcal glomerulonephritis ... #Classification
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... cryoglobulinemias (types ... #diagnosis #glomerulonephritis ... nephrotic #nephritic #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis - Skin, glomeruli ... Urticaria and hypocomplementemia ... : - Kidneys: glomerular ... against MPO • Complement ... #rheumatology #classification
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Kidney Injury - Classification ... - TTP/HUS • Glomerular ... Post-infectious glomerulonephritis ... Kidney #Injury #Classification ... #diagnosis #nephrology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of types ... antigens, leading to complement ... they activate complement ... Post-streptococcal glomerulonephritis ... allergy #table #classification