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diagnosis rheumatology lupus differential management druginduced erythematosus systemic causes clinicopathology comparison criteria dil eularacr hematology hypomagnesemia hypomg laboratory magnesium polycythemia
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... in >90% - Low ... complement - Rare ... complement - 50 ... #comparison #table
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... • Immunologic Workup ... Positive in 60-80% of cases ... 60-80% - Low ... complement - 50
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... > 0.5 g/24 hr, Class ... lupus nephritis, Class ... anticoagulant • Complement ... #Criteria #SLE
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
Excessive GI losses ... Differential #Diagnosis #Low ... #Magnesium #Table ... #Classification ... #Causes #Workup
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... against MPO • Complement ... (Low levels mixed ... vasculitis, and SLE ... #rheumatology #classification
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... some time, let’s see ... levels: realllly low ... you’ll do a good workup ... #workup #hematology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
10% of all lupus cases ... is rare in DIL, SCLE-DIL ... • Immunologic Workup ... in >90% - Low ... complement - Rare
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
should use this algorithm ... risk of smallpox –low ... specimens from low ... See table below ... all HIGH RISK CASES
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