12 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... #Low #Complement ... Mnemonic #diagnosis #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Disease 3 Types ... originate from a low-grade ... lymphoproliferative disorder ... younger pts) Differential ... temperatures by fixing complement
Shock Classification and Differential Diagnosis
SHOCK
 • MAP <65, SBP <90, drop in SBP > 40
 •
Shock Classification ... and Differential ... Medications, Spinal Cord ... #Differential # ... Diagnosis #Types
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
hematological disorders ... to Autoimmune Disorders ... factor level • Low ... serum C4 complement ... #classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential ... Diagnosis Algorithm ... B-Cell ~90% • Low ... #Classification ... #algorithm
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... • This pattern could ... (either severe Type ... 1 or Type 3) — ... differentiate vWD
Factors that May Affect Fetal Oxygenation - Differential Diagnosis Algorithm

Excessive Uterine Activity:
 • Hyperstimulation
 • Placental
Oxygenation - Differential ... Diagnosis Algorithm ... Uterine Blood Flow ... Vasculopathy (SLE, Type ... #Diagnosis #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed ... #rheumatology #classification
Causes of Secondary Amenorrhea - Differential Diagnosis Algorithm
Absence of menses for more than 3 cycles or
Secondary Amenorrhea - Differential ... Diagnosis Algorithm ... failure (<35 years old ... FSH, Low estrogen ... Functional (e.g. eating disorder
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... Skin Disease Classification ... permanent alopecia Differential ... Kikuchi disease • Type-I