8 results
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
Suggested algorithm ... for bone marrow biopsy ... low-risk MGUS (IgG type ... are no clinical features ... #management #hematology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Lymphoproliferative Disorders ... Diagnosis and classification ... : tissue biopsy ... Lymphoproliferative #Disorders ... oncology #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... -95% of cases) Classification ... immunophenotypic features ... lymphoma #diagnosis #classification ... hematology #oncology #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... Kikuchi disease • Type-I ... RNP antibodies, Complement ... SLE • Kidney biopsy
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
• Pancreas: Type ... - ↑ IgE, ↓ complement ... • Classification ... mimics excluded MANAGEMENT ... IGG4 #Diagnosis #Management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
salivary gland) biopsy ... Cytopenia: 2% • Hypocomplementemia ... salivary gland) biopsy ... ducts Clinical Features ... Rheumatology #Diagnosis #Management
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
or plasma cell disorder ... undergoing kidney biopsy ... guide subtype classification ... tubulopathy) - Complement ... vasculitis Types
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
LCH is a rare disorder ... Langerhans cells, a type ... : LCH exhibits features ... • Biopsy: Confirmation ... Histiocytosis #Diagnosis #Management