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diagnosis anemia hematology differential agglutinin aiha causes disease extravascular hemolysis intravascular testing warm workup
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Warm vs Cold Autoimmune ... Immunosuppression, Splenectomy Cold ... Autoimmune Hemolytic ... BostonChiefs #Warm #Cold ... #Autoimmune #Hemolytic
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Differential Diagnosis Algorithm ... Warm AIHA • Cold ... AIHA • Alloimmune ... perfringens - Complement-Mediated ... • Cold AIHA
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... Cold Agglutinins ... Viral infection, autoimmune ... CLL (older) • Autoimmune ... temperatures by fixing complement
Autoimmune Hemolytic Anemia (AIHA) WARM AHA - Primary - Idiopathics - Secondary Infectious • Viral- HIV, EBV, HCV, HEV •
Autoimmune Hemolytic ... Non-Hodgkin Lymphoma Autoimmune ... alpha-methyldopa COLD ... #Hemolytic #Anemia ... #Differential #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Agglutination - Cold ... elliptocytosis, autoimmune ... Differential #Diagnosis #Algorithm
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