55 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... With associated pulmonary ... involvement: Anti-GBM Disease ... differential #diagnosis #algorithm
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal ... anti-GBM) 10%: - Low Complement ... Vasculitis - Normal Complement ... , mitral valve disease ... Kumfer @AnnKumfer #Pulmonary
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
progressing GN • New pulmonary ... glomerulonephritis and/or pulmonary ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement
Diagnostic algorithm for a child or adolescent with suspected pulmonary hypertension. CHD, congenital heart disease; CPET,
Diagnostic algorithm ... congenital heart disease ... veno-occlusive disease ... , chronic lung disease ... Hypertension #Workup #Algorithm
Pulmonary Function Tests (PFTs) - Interpretation Algorithm
 • Normal
 • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia
 • Chest
Pulmonary Function ... Interpretation Algorithm ... • Normal • Pulmonary ... Interstitial Lung Disease ... Interpretation #Algorithm
Diagnostic algorithm for idiopathic pulmonary fibrosis, in part adapted from the ATS/ERS consensus statement. HRCT =
Diagnostic algorithm ... for idiopathic pulmonary ... interstitial lung disease ... IPF = idiopathic pulmonary ... #IPF #UIP #Algorithm
Causes of Hypoxemia- Differential Diagnosis Algorithm
Ventilation/perfusion Mismatch
 • Airway Disease (Asthma, COPD)
 • Vascular (PE*)
 •
Differential Diagnosis Algorithm ... Mismatch • Airway Disease ... • Parenchymal Disease ... • Pulmonary Arterial ... Differential #Diagnosis #Algorithm
Pulmonary Function Testing (PFT) Interpretation Algorithm

Restrictive Lung Disease:
 • Chest wall or neuromuscular disorders
 • Interstitial
Pulmonary Function ... Interpretation Algorithm ... Restrictive Lung Disease ... MatthewHoMD #Pulmonary ... Interpretation #Algorithm
Causes of Dyspnea - Differential Diagnosis Algorithm
Cardiac:
 • Dysrhythmia
 • Ischemia
 • Cardiomyopathy
 • Valvular disease
Differential Diagnosis Algorithm ... Cardiomyopathy • Valvular disease ... disease • Asthma ... Interstitial lung disease ... Differential #Diagnosis #Algorithm