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diagnosis differential causes hemolytic rheumatology workup agglutinin classification cold disease erythematosus extravascular fuo hemolysis immunecompromised immunocompromised intravascular lupus sle systemic
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Differential Diagnosis Algorithm ... perfringens - Complement-Mediated ... immune-complex hemolytic anemia ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Refer to your ‘Fever ... Returning Traveler’ algorithm ... smear • Signs of VTE ... values supporting hematologic
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... bartonella (oroya fever ... ARUPLabs #Hemolytic #Anemia ... #workup #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... Coronary arteries - Fever ... Vasculitis: • Fevers ... against MPO • Complement
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... temperatures by fixing complement ... Symptoms: High fevers ... #hematology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... anti-Smith Ab, low complements ... lymphopenia, low PLT • Anemia ... to: Arthritis, Fever ... RNP antibodies, Complement
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Differential Diagnosis Algorithm ... Periodontal Disease Complement ... Infection #Fever ... #Causes #Hematology
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