7 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Complex Formation - Complement ... Cytokines, Mast Cells ... perivascular inflammatory cells ... Pathophysiology #Rheumatology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... they activate complement ... types #allergy #table ... #classification ... #comparison
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... episcleritis as well ... against MPO • Complement ... #classification
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
of IgG4+ plasma cells ... aortitis, mimics vasculitis ... - ↑ IgE, ↓ complement ... • Classification ... Diagnosis #Management #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... Angioimmunoblastic T-cell ... RNP antibodies, Complement ... : • Chronic B-cell
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
Well-circumscribed ... of necrotizing vasculitis ... PrathitKulkarni #Erythemas #comparison ... #table #differential ... #diagnosis #dermatology
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
meet criteria for hematologic ... or evolve into hematologic ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis