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diagnosis differential rheumatology lupus erythematosus vasculitis causes central champs comparison criteria cryoglobulinemia cryoglobulins disorders druginduced eularacr low lymphomas lymphoproliferative maculopapular
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis (>90%) S - Systemic ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... #differential #hematology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... pericarditis • Hematologic ... anticoagulant • Complement ... #Criteria #SLE
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... months to years) Systemic ... 80% - Low complement ... #comparison #table ... #rheumatology #
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... Abnormality • SLE ... Grooves • Any systemic ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... vasculitis, and SLE ... #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... Skin Disease Classification ... RNP antibodies, Complement ... #Systemic #Lupus
Maculopapular Rashes - THE ALGORITHMIC APPROACH The term maculopapule is a portmanteau, a combination of macule and
Maculopapular Rashes - THE ALGORITHMIC ... macule and papule (Table ... of the rash and systemic ... #Diagnosis #Dermatology ... Maculopapular #Rash #Algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... site in lymphatic system ... with lymphatic system ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • Low serum C4 complement ... erythematosus (SLE ... diagnosis #types #classification ... #rheumatology #
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... frequently affected systems ... Better call hematology ... some time, let’s see ... #workup #hematology
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