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diagnosis rheumatology differential druginduced erythematosus nephritis nephrology systemic treatment vasculitis bronchiectasis classes comparison cryoglobulinemia cryoglobulins dil high hyperkalemia potassium pulmonary
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Proliferative Class IV - Diffuse ... #Nephritis #SLE ... #Classification ... #Classes #differential ... #diagnosis #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... Discontinuation of causal ... 80% - Low complement ... Usual therapeutic management ... rheumatology #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... , oral ulcers, Lupus ... Positive in 60-80% of cases ... 80% - Low complement
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... in 10 to 40% of SLE ... by 12 months Classification ... • Class IV - Diffuse ... glomeruli) Diffuse
Bronchiectasis: diagnosis and management Causes of localized -> diffuse bronchiectasis Foreign body, Bronchial stenosis (tumor, .. ),
diagnosis and management ... Causes of localized ... -> diffuse bronchiectasis ... RA, Sjögren, SLE ... Differential #workup #algorithm
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... Skin Disease Classification ... pneumonitis • Diffuse ... enteropathy, and diffuse
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... such as systemic lupus ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... (e.g. systemic lupus ... diagnosis #types #classification
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... is rare in DIL, SCLE-DIL ... 90% - Low complement ... Discontinuation of causal ... diagnosis #treatment #management
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... diseases: syßtemic lupus ... erythematosus (SLE ... High #Potassium #Classification ... #Causes
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