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diagnosis nephrology rheumatology differential sle treatment comparison erythematosus systemic table alopecia causes classes classification dermatology diseases druginduced glomerular glomerulonephritis hairloss
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus Nephritis ... Proliferative Class Ill - Focal ... Proliferative Class IV - Diffuse ... #Nephritis #SLE ... differential #diagnosis #management
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... • Class Ill - Focal ... • Class IV - Diffuse ... #Nephritis #Management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... pneumonitis • Diffuse ... enteropathy, and diffuse ... RNP antibodies, Complement ... suspicion for nephritis
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Diagnosis Algorithm ... DIFFUSE Scarring ... Irreversible-biopsy required • Lupus ... • Discoid lupus ... Differential #Diagnosis #Algorithm
Algorithm for the Treatment of Membranous Lupus Nephritis Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... of Membranous Lupus ... #Membranous #Lupus ... #Nephritis #Algorithm ... #Treatment #management
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Post-strep GN, Lupus ... Nephritis, Cryoglobulinemia ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... , oral ulcers, Lupus ... nephritis, NPSLE ... 80% - Low complement
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... nephritis, NPSLE ... 80% - Low complement ... Usual therapeutic management ... rheumatology #diagnosis #management
Lupus Nephritis Treatment Algorithm DOI: 10.1159/000511268 #Lupus #Nephritis #Treatment #Algorithm #management #nephrology
Lupus Nephritis ... Treatment Algorithm ... 10.1159/000511268 #Lupus ... #Nephritis #Treatment ... #Algorithm #management
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
EM) Haematuria/nephritis ... • Lupus ISN/RPS ... class IV (diffuse ... Haemolytic-uraemic syndrome Nephrotic ... change disease • Focal
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