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diagnosis rheumatology differential druginduced erythematosus renal systemic vasculitis bronchiectasis classification comparison copd crrt dil glomerulonephritis gold gold2019 guidelines managment mimics
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... , oral ulcers, Lupus ... 60-80% - Low ... complement - 50
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
in >90% - Low ... complement - Rare ... 60-80% - Low ... complement - 50 ... Usual therapeutic management
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal ... Diagnosis Framework Diffuse ... anti-GBM) 10%: - Low ... Complement Levels ... : SLE, Cryoglobulinemic
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low ... Complement: Post-strep ... GN, Lupus Nephritis ... With associated pulmonary ... differential #diagnosis #algorithm
Bronchiectasis: diagnosis and management Causes of localized -> diffuse bronchiectasis Foreign body, Bronchial stenosis (tumor, .. ),
diagnosis and management ... of localized -> diffuse ... RA, Sjögren, SLE ... Differential #workup #algorithm ... #pulmonary
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low ... complements and ... pneumonitis • Diffuse ... , lymphopenia, low
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... (Low levels mixed ... vasculitis, and SLE
Renal Replacement Therapy (RRT) - ICU One Pager Summary Indications (AIEOU): • A: Acidosis (usually severe metabolic)
valproate, etc); see ... Fluid Overload (pulmonary ... SLEDD (Sustained low ... Provides diffusive ... #Therapy #RRT #managment
COPD Management Algorithm - GOLD 2019 guidelines Categorize into COPD GOLD A-D -> Initiate first-line therapy
COPD Management ... Algorithm - GOLD ... See one of my previous ... posts about how ... #Pulmonary #Algorithm
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... is rare in DIL, SCLE-DIL ... in >90% - Low ... complement - Rare ... diagnosis #treatment #management
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