11 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... 1 (50%-80%), type ... S - Systemic Lupus ... Erythematosus (total 50, renal ... #Low #Complement
Lupus Nephritis Classification Algorithm

#Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... Classification Algorithm ... #Classification ... #differential #types ... rheumatology #nephrology #renal
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... antigens, leading to complement ... they activate complement ... glomerulonephritis, Systemic lupus ... #table #classification
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... hemolysis • Renal ... anticoagulant • Complement ... C3 or low C4, Low ... #EULARACR #Classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
antigen, leading to complement ... Complement activation ... , and systemic lupus ... #Classification ... Allergy #Diagnosis #Reactions
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... disease, drug reactions ... against MPO • Complement ... (Low levels mixed ... #rheumatology #classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types: • Type ... factor level • Low ... serum C4 complement ... (e.g. systemic lupus ... #classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... Skin Disease Classification ... Kikuchi disease • Type-I ... APLA/LAC: • Renal
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
diseases: syßtemic lupus ... Pseudohypoaldosteronism type ... pseudohypoaldosteronism type ... Drug-associated: heparin, low-molecular-weight ... High #Potassium #Classification
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
Gammopathy of Renal ... guide subtype classification ... Damages Kidneys • Low ... tubulopathy) - Complement ... vasculitis Types