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diagnosis differential rheumatology classification vasculitis causes glomerular glomerulonephritis nephritis nephrotic testing workup champs cryoglobulinemia cryoglobulins disease erythematosus hematology initial metabolicacidosis
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... S - Systemic Lupus ... #Low #Complement
Lupus Nephritis Classification Algorithm #Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... Classification Algorithm ... #Lupus #Nephritis ... #differential #types ... #rheumatology #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low ... Complement: Post-strep ... GN, Lupus Nephritis ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types: • Type ... • Type III Often ... factor level • Low ... serum C4 complement ... (e.g. systemic lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Urticaria and hypocomplementemia ... inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... (Low levels mixed
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... Kikuchi disease • Type-I ... , lymphopenia, low ... RNP antibodies, Complement
Causes of Nephrolithiasis - Differential Diagnosis Algorithm Radio-opaque - Calcium-containing - 90% of stones Radiolucent - Non-calcium 10%
Differential Diagnosis Algorithm ... overproduction • Low ... solubility: • Low ... Hypocitraturia • RTA Type ... Nephrolithiasis #Nephrology
Causes of Non-Gap Metabolic Acidosis - Differential Diagnosis Algorithm Normal Anion Gap (<14) (Loss of Bicarbonate) -
Differential Diagnosis Algorithm ... Cell Problem - Low ... TTKG • RTA Type ... MetabolicAcidosis #NonGap #Nephrology ... Differential #Diagnosis #Algorithm
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
in monitoring low-level ... or alternative complement ... cryoglobulinemias (types ... nephrotic #nephritic #nephrology
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
in monitoring low-level ... or alternative complement ... cryoglobulinemias (types ... initial #testing #nephrology
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