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differential neurology rheumatology aki acute injury kidney lupus management nephritis workup glomerular glomerulonephritis nephrotic testing weakness acutekidneyinjury biopsy classes clinicopathology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Urticaria and hypocomplementemia ... against MPO • Complement ... , and SLE) • Urinalysis ... #rheumatology #classification
Causes of Polyneuropathy - Differential Diagnosis Algorithm • Metabolic: DM, Hypothyroidism, CKD, Cirrhosis, Nutritional deficiency •
Causes of Polyneuropathy ... Paraneoplastic, CTD (SLE ... RA, Sjogren’s), Vasculitis ... #Algorithm #causes ... #neurology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Autoimmune • ITP • SLE ... HUS • DIC • Vasculitis ... #Algorithm #Causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Labs/Diagnosis: ... • Low serum C4 complement ... #types #classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Glomerulonephritis #Vasculitis ... #differential #diagnosis ... #algorithm #rheumatology
Causes of Peripheral Weakness with Sensory Changes - Differential Diagnosis Algorithm Radiculopathy: • Disc • Spondylosis •
Causes of Peripheral ... - Differential Diagnosis ... Algorithm Radiculopathy ... Multiplex: • Vasculitis ... #Algorithm #Causes
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Causes of Seizures ... Algorithm Unprovoked ... malformation, Aneurysm, Vasculitis ... #Algorithm #Causes ... #neurology
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Kidney Injury - Classification ... - Small vessel vasculitis ... tubular necrosis (causes ... Kidney #Injury #Classification ... #diagnosis #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Algorithm Persistent ... (MPA) • SLE ... #Proteinuria #Nephrology ... #Algorithm #Causes
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus #Nephritis #SLE ... #Classification ... #Classes #differential ... #diagnosis #management ... #nephrology
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