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diagnosis rheumatology lupus management systemic vasculitis alcohol comparison cryoglobulinemia cryoglobulins differential druginduced etoh gammopathy mgrs monoclonal monotherapy phenobarbital protocol pulmcrit
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... Positive in 60-80% of cases ... 80% - Low complement ... lupus #Systemic #Erythematosus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... Skin Disease Classification ... ) • Endocrine disorders ... RNP antibodies, Complement
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... 90% - Low complement ... Discontinuation of causal ... Systemic Lupus Erythematosus ... • Immunologic Workup
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... systemic lupus erythematosus ... diagnosis #types #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... systemic lupus erythematosus ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
Phenobarbital monotherapy algorithm for alcohol withdrawal ** EDIT - SEE UPDATED ALGORITHM HERE: https://www.grepmed.com/images/4060/phenobarbital-monotherapy-withdrawal-management-algorithm-protocol-pulmcrit -Phenobarbital monotherapy has numerous advantages
withdrawal ** EDIT - SEE ... UPDATED ALGORITHM ... Alternative causes ... the underlying disorder ... -If you work at
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 Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... or plasma cell disorder ... Diagnostic Workup ... guide subtype classification ... tubulopathy) - Complement
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