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diagnosis rheumatology differential erythematosus criteria cryoglobulinemia cryoglobulins eularacr indications management nephritis nephrology sjogrens syndrome types vasculitides
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... lupus erythematosus ... against MPO • Complement ... , and SLE) • Urinalysis ... #rheumatology #classification
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... anticoagulant • Complement ... #Criteria #SLE ... #Systemic #Lupus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... Skin Disease Classification ... • Kidney biopsy ... #Systemic #Lupus
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • Low serum C4 complement ... lupus erythematosus ... (SLE), rheumatoid ... diagnosis #types #classification
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE) SLE patient develops
Lupus Nephritis ... associated with systemic ... Perform Kidney Biopsy ... Nephritis #diagnosis #algorithm ... #biopsy #indications
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... diseases, such as SLE ... ESR > 50mm/hr • Biopsy ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary gland) biopsy ... Cytopenia: 2% • Hypocomplementemia ... salivary gland) biopsy ... Vasculitis: •
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