10 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... Myopathy (Also caused ... #MSK #Musculoskeletal ... pathophysiology #signs
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... Discontinuation of causal ... months to years) Systemic ... 80% - Low complement ... #comparison #table
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
Causes of ileitis ... infections include systemic ... See below for table ... helpful paper complements ... #Differential #Table
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Urticaria and hypocomplementemia ... purpura: strong sign ... against MPO • Complement ... vasculitis, and SLE
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs ... conditions: Autoimmune (SLE ... features: Fever -, Systemic ... in up to 30% of cases ... Marantic #diagnosis #table
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... purpura: Strong sign ... tract, and often causes ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
the lymphatic system ... symptoms are not caused ... anterior/posterior MSK ... 5-10%, nervous system ... Diagnosis #Management #Signs
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... an underlying cause ... frequently affected systems ... some time, let’s see ... Differential #Diagnosis #Algorithm
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
• Symptoms and signs ... Non-compressive Spinal Cord Causes ... Behcet disease - SLE ... , Scleroderma, Systemic ... differential #algorithm
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Cytopenia: 2% • Hypocomplementemia ... • Can cause TYPE ... Central nervous system ... phenomenon (16%) MSK