41 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis (>90%) S - Systemic ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Systemic Lupus Erythematosus (SLE): Pathogenesis

 • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
(SLE): Pathogenesis ... HLA-DR3 genes, complement ... self-antigens, activating complement ... cytokines such as ... Erythematosus #SLE
Causes of Vaginal Discharge - Differential Diagnosis Algorithm
Neoplastic:
 • Endometrium
 • Cervix
 • Vulva
 • Vagina
Systemic
Causes of Vaginal ... Differential Diagnosis Algorithm ... Vulva • Vagina Systemic ... #Causes #Gynecology ... #OBGyn
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... Positive in 60-80% of cases ... 80% - Low complement ... #lupus #Systemic
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs ... 90% - Low complement ... Discontinuation of causal ... months to years) Systemic ... 80% - Low complement
Causes of Pelvic Mass - Differential Diagnosis Algorithm
Gastrointestinal:
 • Appendiceal abscess
 • Diverticular abscess
 • Diverticulosis
Causes of Pelvic ... Differential Diagnosis Algorithm ... Hydrosalpinx Ovary: • See ... #Causes #Gynecology ... #OBGyn
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
Causes of ileitis ... infections include systemic ... and amyloidosis as ... See below for table ... helpful paper complements
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... vasculitis, and SLE
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... antibody positivity, as ... anticoagulant - Low complement ... #Rheumatology #SLE
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... Abnormality • SLE ... Grooves • Any systemic ... Differential #Diagnosis #Algorithm ... #causes