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diagnosis rheumatology classification erythematosus allergy associations differential hypersensitivity pathophysiology reactions types autoantibodies connectivetissuediseases criteria ctild druginduced eularacr lungdisease management pulmonary
Systemic Lupus Erythematosus (SLE): Pathogenesis • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Systemic Lupus Erythematosus ... (SLE): Pathogenesis ... HLA-DR3 genes, complement ... -6, IL-10 #Systemic ... #Lupus #Erythematosus
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
rheumatoid arthritis SLE ... : systemic lupus ... ConnectiveTissueDiseases #ILD ... #Differential #Comparison ... #Table #Pulmonary
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... Prognosis: Usually mild ... months to years) Systemic ... #sle #comparison ... #table #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Classification Criteria for Systemic ... nephritis, Class Ill ... anticoagulant • Complement ... Classification #Criteria #SLE ... #Systemic #Lupus
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus ... (SLE): ANA (anti-nuclear ... • Scleroderma (Systemic ... RNA Polymerase Ill ... #associations #table
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... CNS • Headache, mild ... RNP antibodies, Complement ... #Systemic #Lupus
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... Type Ill - IgG and ... Complement activation ... lupus erythematosus ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... glomerulonephritis, Systemic ... lupus erythematosus ... types #allergy #table ... classification #comparison
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Urticaria and hypocomplementemia ... inflammation Others: • Lupus ... lupus erythematosus ... against MPO • Complement ... vasculitis, and SLE
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