12 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... 90% - Low complement ... Discontinuation of causal ... • Immunologic Workup ... 80% - Low complement
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... practices that could cause ... smear, HIV/HCV testing ... test, ANA (e.g., SLE ... #Workup #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... are evocative of SLE ... • Immunologic Workup ... Positive in 60-80% of cases ... 80% - Low complement
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... infections are common causes ... #glomerular #testing ... #workup #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... vasculitis, and SLE
Intraoperative Massive Blood Loss - Guidelines for Crises in Anaesthesia
Expected or unexpected major haemorrhage

❶ Call for
Guidelines for Crises ... interventional radiology ... point of care testing ... • Use lab testing ... Diagnosis #Management #Workup
Constrictive Pericarditis on Echocardiogram
A 55-year-old female marathon runner presents to clinic w/ 6-months of worsening breathlessness
She had gained 15 ... echocardiogram to workup ... expiration not meeting ... pocus #clinical #cardiology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... infections are common causes ... glomerular #disease #workup ... diagnosis #initial #testing
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
10% of all lupus cases ... is rare in DIL, SCLE-DIL ... • Immunologic Workup ... 90% - Low complement ... Discontinuation of causal
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... Treat underlying cause ... interventional radiology ... for possible stenting