10 results
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Nephritis Primer Class ... Lupus #Nephritis #SLE ... #Classification ... #diagnosis #management ... #nephrology
Hypernatremia Management Algorithm
Acute vs Chronic
Calculate Losses
 • Current water Deficit
 • Ongoing Free water Losses
 •
Hypernatremia Management ... Algorithm Acute ... Hypernatremia #Management ... #Algorithm #treatment ... #nephrology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Positive in 60-80% of cases ... 80% - Low complement ... life-threatening • Treatment ... Usual therapeutic management
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... severity (ISN/RPS classification ... by 12 months Classification ... #treatment #management ... #rheumatology #nephrology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... constitutional symptoms • Treatment ... 80% - Low complement ... life-threatening • Treatment ... Usual therapeutic management
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... Treatment of Membranous ... treat non-renal SLE ... #Treatment #management ... #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Urticaria and hypocomplementemia ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
Treatment Algorithm for Active Proliferative Lupus Nephritis (Class III/IV or Mixed Class III/IV + V)
Induction Therapy
Treatment Algorithm ... Lupus Nephritis (Class ... III/IV or Mixed Class ... Lupus #Nephritis #management ... #nephrology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Evaluate for NMO, SLE ... Disorders: - SLE ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management ... #neurology #differential
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
10% of all lupus cases ... is rare in DIL, SCLE-DIL ... 90% - Low complement ... rheumatology #diagnosis #treatment ... #management