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diagnosis rheumatology lupus sle vasculitis anemia causes champs clinicopathology criticalcare disorders druginduced erythematosus findings glomerulonephritis inflammatory laboratory lymphomas lymphoproliferative management
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... Mnemonic #diagnosis #differential ... #hematology
Shock - Findings, Signs and Symptoms by Classification - Hypovolemic (Intravascular volume depletion) - Distributive (Vasodilation)
and Symptoms by Classification ... obstruction to blood flow ... DrEricStrong #Shock #Differential ... #Table #CriticalCare ... Symptoms #Findings #Comparison
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low ... Complement: Post-strep ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Low Mean Corpuscular ... #Anemia #MCV #Classification ... #Causes #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... B-Cell ~90% • Low ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology ... #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed ... #classification
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
in >90% - Low ... complement - Rare ... complement - 50 ... druginduced #lupus #sle #comparison ... #table #rheumatology
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Onset: Insidious/slow ... Inflammatory #Myopathies #differential ... #diagnosis #comparison ... #rheumatology # ... table
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... Skin Disease Classification ... permanent alopecia Differential ... , lymphopenia, low
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
monkeypox virus or to differentiate ... should use this algorithm ... risk of smallpox –low ... specimens from low ... See table below
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