12 results
diagnosis differential hematology rheumatology vasculitis causes classification genetics iem inbornerrors management metabolism neonatology nicu pediatrics peds allergy champs coccidioidomycosis erythematosus
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... of Hypocomplementemic ... Complex Formation - Complement ... Urticarial #Vasculitis #HUV ... #Pathophysiology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... A - Atypical HUS ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table • Thrombotic Thrombocytopenic Purpura (TTP)
Differential Diagnosis Table ... Toxin-Mediated HUS ... (ST-HUS) • Atypical ... HUS (aHUS) ... - Complement-mediated
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
schema of the pathophysiology ... connections and pathophysiology ... the lab values table ... #Diagnosis #Algorithm ... Peds #Pediatrics #Table
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Systemic Lupus Erythematosus (SLE): Pathogenesis • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
HLA-DR3 genes, complement ... Environmental factors: UV-light ... (UV-A, UV-B); Viruses ... self-antigens, activating complement ... Erythematosus #SLE #Pathophysiology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Differential Diagnosis Algorithm ... perfringens - Complement-Mediated ... MAHA (TTP, DIC, HUS ... Differential #Diagnosis #Algorithm
Lab patterns seen in Inborn Errors of Metabolism A table of lab values compiled from UpToDate and
Metabolism A table ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... Peds #Pediatrics #Table
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... Cryoglobulins • HIV ... • HBV HCV •
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
antigen, leading to complement ... Complement activation ... Classification #Pathophysiology ... Diagnosis #Reactions #Table
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