11 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low ... Complement: Post-strep ... GN, Lupus Nephritis ... differential #diagnosis #algorithm
Suggested diagnostic approach to a patient with exudative ascites. Low ascitic fluid protein should direct practitioners
Low ascitic fluid ... syndrome as a cause ... Although nonhepatic causes ... ascites #diagnosis #workup ... #algorithm #differential
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
10% of all lupus cases ... Discontinuation of causal ... ulcers, Lupus nephritis ... Positive in 60-80% of cases ... sle #comparison #table
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Excessive GI losses ... Differential #Diagnosis #Low ... #Magnesium #Table ... #Classification ... #Causes #Workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
ulcers, Lupus nephritis ... • Immunologic Workup ... Positive in 60-80% of cases ... 60-80% - Low ... complement - 50
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
in monitoring low-level ... or alternative complement ... infections are common causes ... glomerular #testing #workup ... #nephritic #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... can be high or low ... failure, Cirrhosis, Nephrotic ... differential #diagnosis #table
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
in monitoring low-level ... or alternative complement ... infections are common causes ... glomerular #disease #workup ... #nephritis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed ... #rheumatology #classification
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
by nephrotoxic ... Diagnostic Workup ... guide subtype classification ... Damages Kidneys • Low ... tubulopathy) - Complement