138 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... of Hypocomplementemic ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic ... Vasculitis #HUV #Pathophysiology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Pathogenesis and Clinical ... dead tissue • Complement ... activation of complement ... #Inflammation #pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... staining): • Low Complement ... Idiopathic • Normal Complement
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
Pathogenesis and Clinical ... infections • Clinical ... response: The complement ... cell membranes -> Critical ... #pathophysiology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-induced edema is caused ... Activation of the complement ... Edema #Medication #Causes ... #Pharmacology #Pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
antigen, leading to complement ... Complement activation ... Classification #Pathophysiology ... Diagnosis #Reactions #Table
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... activation • Complement ... tagged with C3 complement ... - Activate Complement ... Humoral #Immunity #pathophysiology
Clinical Presentation and Diagnosis of Common Causes of Vaginitis

#Vaginitis #Differential #Diagnosis #Comparison #Table #Testing #Gynecology #OBGyn
Clinical Presentation ... Diagnosis of Common Causes ... Diagnosis #Comparison #Table
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... Allergen-specific lgE causes ... antigens, leading to complement ... they activate complement ... types #allergy #table