12 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
blood types or during ... Complement activation ... systemic lupus erythematosus ... Hypersensitivity #Types #Classification ... Diagnosis #Reactions #Table
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Systemic Lupus Erythematosus ... Clinical Domains ... anticoagulant • Complement ... #EULARACR #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... they activate complement ... Systemic lupus erythematosus ... types #allergy #table ... #classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... anti-Smith Ab, low complements ... Skin Disease Classification ... lymphoproliferative syndrome Clinical ... RNP antibodies, Complement
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Urticaria and hypocomplementemia ... ischemia - Skin: erythematous ... systemic lupus erythematosus ... against MPO • Complement ... #rheumatology #classification
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 90% - Low complement ... Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... sle #comparison #table
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... • Low serum C4 complement ... systemic lupus erythematosus ... diagnosis #types #classification
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
also be measured using ... -15% If SLE is clinically ... Systemic #lupus #erythematosus ... #rheumatology #table
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
just simply a clinical ... range of possible clinical ... then be excreted using ... #differential #algorithm ... cardiology #treatment #table
Perhaps quite too often, the knee-jerk reaction to an elevated Troponin is to call our friends
are typically able ... blood flow occurs during ... Even during the ... #diagnosis #algorithm ... echocardiogram #management #clinical