83 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal ... anti-GBM) 10%: - Low Complement ... Vasculitis - Normal Complement ... Kumfer @AnnKumfer #Pulmonary
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... With associated pulmonary
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Differential Diagnosis Table ... HUS (aHUS) - Complement-mediated
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
progressing GN • New pulmonary ... glomerulonephritis and/or pulmonary ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... antigens, leading to complement ... they activate complement ... types #allergy #table
Lung Auscultation and Physical Exam Findings in Selected Lung Disorders

#PhysicalExam #Auscultation #Pulmonary #Percussion #Dullness #Fremitus #BreathSounds
#Auscultation #Pulmonary ... Transmitted #Comparison #Table
Characteristics of Important Exudative Pleural Effusions

#Exudative #Pleural #Effusions #Comparison #Table #Characteristics #Differential #Pulmonary
Effusions #Comparison #Table ... #Differential #Pulmonary
Table of Breathing Patterns and Their Associated Conditions
Apnea
Biot's respirations
Bradypnea
Cheyne-Stokes respirations	
Hyperpnea
Hyperventilation
Hypoventilation
Kussmaul respirations
Orthopnea
Paradoxic ventilation
Sighing respirations
Tachypnea
Hoover's sign

#Breathing #Patterns #Diagnosis
Table of Breathing ... Patterns #Diagnosis #Pulmonary ... #Respirations #Table