12 results
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Autoimmune diseases ... • Low serum C4 complement ... diagnosis #types #classification
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Putrid sputum/sour-tasting ... hemorrhage • Treatment ... Diagnosis: • Vasculitis ... #differential #causes
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... for glomerular disease ... or alternative complement ... infections are common causes ... for ANCA-related vasculitis
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
the most common vasculitis ... , Cough • +/-Nausea ... Criteria - Fever lasting ... #KD #vasculitis ... diagnossi #management #treatment
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... infections are common causes ... for ANCA-related vasculitis ... diagnosis #initial #testing
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Cytopenia: 2% • Hypocomplementemia ... • Can cause TYPE ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... Adenocarcinoma Treatment
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... diagnosis and treatment ... elevated, HFE gene testing ... of liver disease ... hemochromatosis #algorithm
Treatment of smallpox patients generally involves supportive care. Vaccination with replication-competent smallpox vaccines (i.e., ACAM2000 and
Treatment of smallpox ... with replication-competent ... the severity of disease ... Treating smallpox ... the virus that causes