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diagnosis differential causes workup hyponatremia hematology low nephrotic neurology sodium allergy anemia blood c1inh classification disease druginduced esterase glomerulonephritis hematuria
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Skin, glomeruli ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... : - Kidneys: glomerular ... against MPO • Complement
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... for ANCA-related vasculitis ... #testing #workup ... nephrotic #nephritic #nephrology
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... deficiency • Low ... #Deficiency #Testing ... #Algorithm #hematology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
ANCA-positive vasculitis ... ANCA-negative vasculitis ... sclerosis • Anti-Glomerular ... Disease-specific testing ... differential #diagnosis #nephrology
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... mimics, repeat testing ... • Evidence of glomerular ... → Refer to Nephrology ... Hematuria #Diagnosis #Algorithm
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Differential Diagnosis Algorithm ... present on repeat testing ... including overnight testing ... • Drugs Glomerular ... #Proteinuria #Nephrology
Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm INDICATIONS FOR TESTING: • Recurrent angioedema (without urticaria) •
Complement 1 esterase ... inhibitor (C1-INH) Deficiency ... Testing Algorithm ... ARUPLabs #C1INH #Complement ... #Testing #Algorithm
Hypophosphatemia Diagnostic Algorithm - GI Losses - Redistribution - 1° HPT - 1° Renal PO4 wasting: Hereditary, TIO, Fanconi Syndrome,
Hypophosphatemia Diagnostic Algorithm ... - 1° Renal PO4 wasting ... glucose - Vitamin D Deficiency ... low #diagnosis #Algorithm ... #differential #nephrology
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Vitamin C • Glomerular ... : Drug induced vasculitis ... differential #diagnosis #algorithm ... #nephrology #Medications
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... ' nucleotidase deficiency ... cardiac valve, vasculitis ... Differential #Diagnosis #Algorithm ... workup #hematology #testing
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