14 results
diagnosis nephrology hematology disease nephrotic rheumatology workup anemia causes glomerulonephritis proteinuria renal syndrome agglutinin aki classification cold druginduced extravascular hemolysis
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... Diagnosis Algorithm ... perfringens - Complement-Mediated ... Extravascular #Differential ... #Diagnosis #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... - Skin, glomeruli ... Urticaria and hypocomplementemia ... : - Kidneys: glomerular ... against MPO • Complement
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... cardiac valve, vasculitis ... #Anemia #Differential ... workup #hematology #testing
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... LDH - Assess for hemolysis ... or alternative complement ... for ANCA-related vasculitis ... #testing #workup
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Positive Coombs testing ... post infectious setting ... younger pts) Differential ... temperatures by fixing complement
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... LDH - Assess for hemolysis ... or alternative complement ... for ANCA-related vasculitis ... diagnosis #initial #testing
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... ANCA-positive vasculitis ... sclerosis • Anti-Glomerular ... Disease-specific testing ... Renal #Syndrome #differential
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Proteinuria - Differential ... Diagnosis Algorithm ... present on repeat testing ... including overnight testing ... • Drugs Glomerular
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Vitamin C • Glomerular ... : Drug induced vasculitis ... #KidneyInjury #differential ... #diagnosis #algorithm
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