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differential hematology anemia disease nephrology nephrotic agglutinin blood classification cold glomerulonephritis hematuria initial nephritic nephritis platelets rheumatology thrombocytosis urine urology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... cardiac valve, vasculitis ... #Algorithm #workup ... #hematology #testing
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... - Skin, glomeruli ... Urticaria and hypocomplementemia ... : - Kidneys: glomerular ... against MPO • Complement
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
LDH - Assess for hemolysis ... or alternative complement ... for ANCA-related vasculitis ... #testing #workup ... #diagnosis #glomerulonephritis
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... and Diagnosis Algorithm ... mimics, repeat testing ... • Evidence of glomerular ... #Algorithm #Workup
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... LDH - Assess for hemolysis ... or alternative complement ... for ANCA-related vasculitis ... #workup #diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Diagnosis: • hemolytic ... Positive Coombs testing ... post infectious setting ... temperatures by fixing complement
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Algorithm Peripheral ... hematology for workup ... blood loss, Acute hemolysis ... Rheumatologic, Vasculitides
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