12 results
diagnosis rheumatology differential management nephrology disease glomerular glomerulonephritis hematology igg4 lupus sle acute aki anemia causes classification comparison druginduced erythematosus
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Post-strep GN, Lupus Nephritis ... • Limited to Kidney ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... Polyarteritis Nodosa: - Kidneys ... Kidneys -> glomerulonephritis ... against MPO • Complement
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... Glomerulonephritis / Vasculits ... • Interstitial nephritis ... #Injury #AKI #Workup
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... for ANCA-related vasculitis ... #glomerular #testing ... #workup #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... ANCA-associated vasculitis ... RNP antibodies, Complement ... C4) • ds-DNA: Kidney ... induced SLE • Kidney
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... for ANCA-related vasculitis ... glomerular #disease #workup ... #nephritis
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
lesions, meninges, kidneys ... rheumatoid factor), ± hypocomplementemia ... No necrosis, No vasculitis ... management #phenotypes #workup
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... cardiac valve, vasculitis ... Differential #Diagnosis #Algorithm ... #workup #hematology ... #testing
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... hematology for workup ... Rheumatologic, Vasculitides ... disease, Kawasaki, Nephrotic ... Differential #Diagnosis #Algorithm
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
myalgia, serositis, Kidney ... • Immunologic Workup ... 90% - Low complement ... ulcers, Lupus nephritis ... • Immunologic Workup
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