8 results
diagnosis rheumatology differential nephrology glomerular glomerulonephritis sle acute aki causes classification comparison disease druginduced erythematosus gammopathy initial injury management mgrs
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Nephritis, Cryoglobulinemia ... • Limited to Kidney ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Urticaria and hypocomplementemia ... inflammation Others: • Lupus ... such as systemic lupus ... Kidneys -> glomerulonephritis ... against MPO • Complement
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... ANCA-associated vasculitis ... RNP antibodies, Complement ... C4) • ds-DNA: Kidney ... induced SLE • Kidney
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
myalgia, serositis, Kidney ... • Immunologic Workup ... 90% - Low complement ... nephritis, NPSLE ... • Immunologic Workup
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... Glomerulonephritis / Vasculits ... • Interstitial nephritis ... #Injury #AKI #Workup
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... for ANCA-related vasculitis ... #glomerular #testing ... #workup #diagnosis
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... for ANCA-related vasculitis ... glomerular #disease #workup ... #nephritis
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
disease caused by nephrotoxic ... Clinical Clues: • Nephrotic-range ... Diagnostic Workup ... tubulopathy) - Complement ... formation causing vasculitis
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