10 results
diagnosis rheumatology differential treatment abscess allergy causes classification coccidioidomycosis comparison disease druginduced fever glomerulonephritis huv hypersensitivity hypocomplementemic infectiousdiseases lung lupus
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... of Hypocomplementemic ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic ... #HUV #Pathophysiology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... node), high serum IgG4 ... rheumatoid factor), ± hypocomplementemia ... No necrosis, No vasculitis ... Disease #diagnosis #management
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
dysfunction PATHOPHYSIOLOGY ... aortitis, mimics vasculitis ... - ↑ IgE, ↓ complement ... mimics excluded MANAGEMENT ... #Management #Rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
antigen, leading to complement ... Type Ill - IgG and ... Complement activation ... Classification #Pathophysiology ... Diagnosis #Reactions #Table
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
- ANA > 95% (IgG ... 90% - Low complement ... 80% - Low complement ... Usual therapeutic management ... sle #comparison #table
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Diagnosis and Management ... Lung Abscess Pathophysiology ... Lung Abscess Management ... Diagnosis: • Vasculitis ... differential #causes #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... - Oligoclonal IgG ... levels • NMO-IgG ... - Sjogren - Vasculitis ... Myelitis #diagnosis #management
Coccidioidomycosis (Valley Fever) - Diagnosis and Management Summary WHAT? • Coccidioidomycosis due to Coccidioides immitis or Coccidioides
Diagnosis and Management ... analysis using complement ... check for IgM and IgG ... TREATMENT: Clinically stable ... Fever #Diagnosis #Management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
ANCA-associated vasculitis ... POEMS syndrome - IGG4 ... cell lymphoma Pathophysiology ... TAFRO #diagnosis #management
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