23 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Urticarial Vasculitis ... Complex Formation - Complement ... Formation -> Vasculitis ... TerrierBen #Hypocomplementemic
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis and Vasculitides ... When to Consider Vasculitis ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types: • Type ... arthritis) • Types ... • Type III Often ... • Low serum C4 complement ... • Vasculitis
Kidney stone type, corresponding urine sediment, urinary risk factors, and associated clinical settings.
#Diagnosis #Nephrology #Urine #Microscopy
Kidney stone type ... #Diagnosis #Nephrology ... Stones #Crystals #Types ... Composition #Shapes #Table
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... Their Mechanisms Type ... antigen, leading to complement ... Complement activation ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... Type 1 - Mediators ... antigens, leading to complement ... they activate complement ... #allergy #table
Renal Tubular Acidosis (RTA) Diagnosis and Management
 • Distal (type 1) RTA
 • Proximal (type 2)
Management • Distal (type ... RTA • Proximal (type ... Hyperkalemic (type ... Diagnosis #Management #nephrology ... #table
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
spondyloarthropathies, vasculitides ... See below for table ... helpful paper complements ... #Differential #Table
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
cryoglobulinemia vasculitis ... neuropathy • Type ... Cryoglobulinemia #Vasculitis ... Cryoglobulinemic #Nephrology