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diagnosis hematology rheumatology vasculitis workup polycythemia aki anemia cancer causes champs classification erythrocytosis fever glomerulonephritis hemolytic hyponatremia igg4 immunecompromised immunocompromised
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... Mnemonic #diagnosis #differential
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... pseudotumor 4 phenotypes ... rheumatoid factor), ± hypocomplementemia ... IgG4 #Related #Disease ... diagnosis #management #phenotypes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... Differential ... against MPO • Complement
HSCT related renal disease - AKI and CKD Acute Kidney Injury: Acute GvHD 2-4, Pre renal state,
HSCT related renal ... body irradiation, Complement ... stemcell #transplant #HSCT ... #AKI #differential ... #diagnosis #algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... (diverse genotypes ... Hemolytic #Anemia #Differential ... #Diagnosis #Algorithm
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
- Polycythemia Differential ... Diagnosis Algorithm ... Cardiac/pulmonary disease ... Polycythemia #Vera #PV #Differential ... #Diagnosis #Algorithm
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic ... #Vasculitis #Differential
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Diagnosis Algorithm ... can drive this disease ... As with many disease ... #Diagnosis #Algorithm
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Immunocompromised Host - Differential ... Diagnosis Algorithm ... • Periodontal Disease ... Complement Deficiency ... #Diagnosis #Algorithm
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