16 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Related Disease Clinical ... pseudotumor 4 phenotypes ... rheumatoid factor), ± hypocomplementemia ... diagnosis #management #phenotypes
Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV)

Diagnosis of HUV
1) Chronic urticaria 
2) Leukocytoclastic vasculitis 
3)
Management of Hypocomplementemic ... vasculitis 3) Hypocomplementemia ... TerrierBen #Hypocomplementemic
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... TerrierBen #Hypocomplementemic
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia
COPD phenotypes:  Blue Bloaters vs. Pink Puffers
The two most stereotypical forms of COPD are pink
COPD phenotypes: ... physiology and clinical ... BlueBloaters #Comparison #Phenotypes
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic
Toluene Poisoning - Diagnosis and Management Summary
What is it?  Volatile hydrocarbon, Glue or paint-sniffing, Occupational
acute or chronic Clinical ... • Distal-RTA phenotype
String Test in Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP)
Hypermucoviscosity (HMV) phenotype is a known virulent factor of
Hypermucoviscosity (HMV) phenotype ... #String #Test #clinical
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
auricular papules Clinical ... prevalence of RP-ILD Phenotype ... Arthralgia/arthritis Phenotype ... muscle weakness Phenotype