22 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... (Granulomatous disease ... against MPO • Complement ... (Low levels mixed
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
staining): • Low ... Complement: Post-strep ... Idiopathic • Normal Complement ... involvement: Anti-GBM Disease ... differential #diagnosis #algorithm
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... rheumatoid factor), ± hypocomplementemia ... IgG4 #Related #Disease ... #diagnosis #management
Graves Hyperthyroidism - Diagnosis and Management Algorithm
Low TSH -> TSH-R-Ab+ -> Graves' Hyperthyroidism

doi: 10.1210/clinem/dgaa646

#Graves #Disease #Hyperthyroidism
Diagnosis and Management ... Algorithm Low TSH ... dgaa646 #Graves #Disease ... Hyperthyroidism #Management ... #Algorithm #treatment
Proposed Respiratory Support Algorithm in COVID19

The ‘intubate early’ paradigm, where patients who “fail” low flow oxygen
Respiratory Support Algorithm ... with COVID lung disease ... this may be the disease ... Also, a low threshold ... support #COVID19 #management
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm

Radioactive iodine scan – get if concern for nodular
Hyperthyroidism (low ... ) - Diagnostic Algorithm ... Graves disease – ... workup choices AND management ... Hyperthyroid #Diagnosis #Algorithm
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... 60-80% - Low ... complement - 50 ... Usual therapeutic management ... Evolution: Chronic disease
Approach to Antithrombotic Therapy in Peripheral Artery Disease
Increased Ischemic Risk:
 • Prior MI
 • Diabetes
 •
Peripheral Artery Disease ... Chronic kidney disease ... • Anemia • Low ... Antithrombotic #management ... #antiplatelet #algorithm
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Diagnosis and Management ... Independent (↑ PTH) • LOW ... Activation: Liver disease ... , Kidney Disease ... #differential #algorithm