26 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Positive in 60-80% of cases ... 60-80% - Low ... complement - 50 ... life-threatening • Treatment
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... be considered “low ... an infant with fever ... #Diagnosis #Management ... Stratification #Fever
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
in >90% - Low ... complement - Rare ... 60-80% - Low ... complement - 50 ... Usual therapeutic management
Visceral Leishmaniasis - Diagnosis and Management Summary
Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi
Where: South Asia, East
Diagnosis and Management ... Neutralization of complement ... 2-6 months • Fever ... Weight Loss • Can cause ... culture, PCR, K39) Treatment
Cyclosporiasis - Diagnosis and Management Summary
Pathogen: 
 • Cyclospora cayetanensis
 • Foodborne, waterbone, and soil-transmitted.
 •
Diagnosis and Management ... sanitation • Low ... • Anorexia, Nausea ... fever, Weight loss ... Treatment: • TMP-SMX-DS
The algorithm below shows how pre-test probability could be combined with various criteria to determine which
patient with a low ... short course of treatment ... provide empiric treatment ... HSV PCR would cause ... is proposed: #Management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - 80% have fever ... , Elevated Cr, Low ... calcium • Treatment ... TLS #diagnosis #management
Emergency Treatment Algorithm for Convulsive Status Epilepticus
1. ABCDEFG (ABC's and Don't Ever Forget the Glucose)
2. Airway:
Emergency Treatment ... Algorithm for Convulsive ... ABC's and Don't Ever ... for reversible cause ... #Algorithm #Management