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diagnosis differential dermatology rheumatology vasculitis ddxof petechiae causes nikolsky petechial c5c9deficiency champs childhood classification color erythematosus erythematous erythroderma febrile glomerulonephritis
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... of Hypocomplementemic ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic ... #Rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... #differential #hematology
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... instability - New-onset fever ... with rash - Mucocutaneous ... #Diagnosis #Dermatology ... #Rash #Maculopapular
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... erythematous rash ... #Diagnosis #Dermatology ... #Erythematous #Rash ... #Algorithm #Nikolsky
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... mucositis - Rash ... Vasculitis: • Fevers ... against MPO • Complement
Vesiculobullous Rashes - THE ALGORITHMIC APPROACH Vesiculobullous rashes provoke significant angst in many physicians (Figure 5, page
Vesiculobullous Rashes - THE ALGORITHMIC ... and a fever may ... localized lesions and fever ... #Diagnosis #Dermatology ... #Algorithm #Differential
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm ... #rheumatology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic Algorithm ... Pathophysiology: ... #Diagnosis #Dermatology ... #Rash #Erythroderma ... #Nikolsky #Algorithm
C5-C9 Deficiency - Pathogenesis and Clinical Findings Note: • Risk of invasive meningococcal disease is 1000-10000x higher
is rare Normal complement ... response: The complement ... tissue -> Fatigue, fever ... Maculopapular rash ... #pathophysiology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial Rash ... Differential Diagnosis Algorithm ... Red Flags: • Fever ... Differential #Diagnosis #Algorithm ... #Causes #dermatology
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