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diagnosis nephrology differential hyponatremia sodium glomerular glomerulonephritis hematology nephrotic rheumatology vasculitis workup amyloid amyloidosis classification deficiency disease hypotonic initial mnemonic
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... - CHAMPS Mnemonic ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... #CHAMPS #Mnemonic
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... in monitoring low-level ... or alternative complement ... #glomerular #testing ... #nephritic #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low ... Complement: Post-strep ... GN, Lupus Nephritis ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... deficiency • Low ... #Deficiency #Testing ... #Algorithm #hematology
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... in monitoring low-level ... or alternative complement ... #nephrology #nephrotic ... #nephritis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
Modified Hyponatremia Algorithm ... failure, Cirrhosis, Nephrotic ... Cerebral salt wasting ... Primary polydipsia, Low ... #Hyponatremia #Algorithm
Volume Based Approach to Hyponatremia Hypovolemic, Serum uric acid >4 • Urine Na <20: Extra-renal losses •
Cerebral salt wasting ... Hypothyroidism, Low ... failure, Cirrhosis, Nephrotic ... #Hyponatremia #algorithm ... diagnosis #sodium #low
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... can be high or low ... Cerebral Salt Wasting ... failure, Cirrhosis, Nephrotic ... Primary polydipsia), Low
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
fibrils formed from low-molecular-weight ... Manifestations: Renal: • Nephrotic ... Cardiac: • LVH, low-voltage ... Immunoglobulin light chains ... typing Cardiac Testing
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