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diagnosis rheumatology management differential huv igg4 urticarial champs cryoglobulinemia cryoglobulins disease erythematosus foraminal gammopathy grading hematology low lumbar lupus mgrs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... gastrointestinal, and/or central ... against MPO • Complement ... #rheumatology #classification
Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV) Diagnosis of HUV 1) Chronic urticaria 2) Leukocytoclastic vasculitis 3)
Management of Hypocomplementemic ... Urticarial Vasculitis ... Leukocytoclastic vasculitis ... 3) Hypocomplementemia ... TerrierBen #Hypocomplementemic
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Urticarial Vasculitis ... Complex Formation - Complement ... Formation -> Vasculitis ... TerrierBen #Hypocomplementemic
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Angiitis of the Central ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic ... gastrointestinal, and/or central
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... Vasculitis Vasculitis ... angiitis of the central ... dermatomyositis #Size #Classification ... #Vasculitis #Vessels
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
rheumatoid factor), ± hypocomplementemia ... No necrosis, No vasculitis
Lumbar stenosis guide we created to implement consistent radiology reporting across our multi-hospital network. Lumbar Central
we created to implement ... Lumbar Central Canal ... Report #Grading #Classification ... #Central #Foraminal
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Low serum C4 complement ... • IgA vasculitis ... • Vasculitis ... diagnosis #types #classification ... #rheumatology #vasculitis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Cytopenia: 2% • Hypocomplementemia ... Xerostomia • Dental ... Involvement: • Central ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis
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