42 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis
Complement Deficiency Testing Algorithm
 • Normal CH50 and AH50 AND High suspicion for complement deficiency
 •
Complement Deficiency ... Testing Algorithm ... #Deficiency #Testing ... #Algorithm #hematology ... #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed
Graves Hyperthyroidism - Diagnosis and Management Algorithm
Low TSH -> TSH-R-Ab+ -> Graves' Hyperthyroidism

doi: 10.1210/clinem/dgaa646

#Graves #Disease #Hyperthyroidism
Hyperthyroidism - Diagnosis ... and Management ... Algorithm Low TSH ... dgaa646 #Graves #Disease ... #Algorithm #treatment
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
staining): • Low ... Complement: Post-strep ... involvement: Anti-GBM Disease ... #differential #diagnosis ... #algorithm #rheumatology
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm

Radioactive iodine scan – get if concern for nodular
Hyperthyroidism (low ... Algorithm Radioactive ... Graves disease – ... workup choices AND management ... #Algorithm #Workup
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... PET-CT Imaging (→ Diagnostic ... rheumatoid factor), ± hypocomplementemia ... IgG4 #Related #Disease ... #diagnosis #management
Lyme Disease Pearls

Epidemiology: Ixodes scapularis carrying borrelia 
have spread and are now found in 
growing areas
Lyme Disease Pearls ... spread and are now ... old is fine #Diagnosis ... #Management #LymeDisease ... #Pearls #Map #Testing
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... 60-80% - Low ... complement - 50 ... Evolution: Chronic disease ... Erythematosus #Diagnosis
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Hypocalcemia - Diagnosis ... and Management ... Independent (↑ PTH) • LOW ... , Kidney Disease ... #differential #algorithm