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diagnosis rheumatology lupus management erythematosus systemic causes druginduced table vasculitis acidosis champs clinicopathology comparison criteria dil elevation eularacr gi hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... Mnemonic #diagnosis #differential
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Nephritis Primer Class ... Proliferative Class ... Lupus #Nephritis #SLE ... #Classification ... #Classes #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
10% of all lupus cases ... calcium-b) • Laboratory ... 90% - Low complement ... versus DIL • Laboratory ... 80% - Low complement
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... are evocative of SLE ... versus DIL • Laboratory ... Positive in 60-80% of cases ... 80% - Low complement
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... > 0.5 g/24 hr, Class ... lupus nephritis, Class ... anticoagulant • Complement ... #Criteria #SLE
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
and fever) and laboratory ... anti-Smith Ab, low complements ... Skin Disease Classification ... permanent alopecia Differential ... with: • Minimal laboratory
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... tract, and often causes ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
Causes of ileitis ... See below for table ... helpful paper complements ... #GI #Ileitis #Differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... again we might see ... - assess other laboratory ... Acidosis #Elevation #Differential ... #typea #typeb #classification
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